Louis-Eugène Varlin (1839-1871)

[Alain Georges: in the footsteps of Louis Pasteur and Eugène Jamot].

The biography of the physician general Alain Jean Georges (1946-2012) shows the exceptional career of a military physician-clinical pathologist specialized in tropical medicine and educated at the Navy Health School in Bordeaux and the Pharo School in Marseille. He completed his education at the Institut Pasteur de Paris in courses still conducted in the spirit of those taught by Louis Pasteur....

Historical vignette: louis emile javal (1839-1907): the father of orthoptics.

Louis Émile Javal was a pioneer in the early history of orthoptics (Figure 1). To anyone knowledgeable about binocular vision, the name Javal conjures up discussions of physiological diplopia, stereoscopes, and fusion training exercises. Javal was a prolific designer of optical devices to use in orthoptic training and ushered in a new era of binocular instrumentation.1–4 Although Wheatstone is ...

Op-cbio160073 1832..1839

Motivation: Large-scale gene expression profiling has been widely used to characterize cellular states in response to various disease conditions, genetic perturbations, etc. Although the cost of whole-genome expression profiles has been dropping steadily, generating a compendium of expression profiling over thousands of samples is still very expensive. Recognizing that gene expressions are ofte...

Ddh197 1839..1848

Human SCO1 and SCO2 are paralogous genes that code for metallochaperone proteins with essential, but poorly understood, roles in copper delivery to cytochrome c oxidase (COX). Mutations in these genes produce tissue-specific COX deficiencies associated with distinct clinical phenotypes, although both are ubiquitously expressed. To investigate the molecular function of the SCO proteins, we chara...

Cases Treated in 1871